Turning Up the Heat on Membrane Fluidity
نویسندگان
چکیده
How do cells maintain the fluidity of cellular membrane in response to temperature fluctuation? In this issue of Cell, Ma et al. identify a regulatory circuit involving a heat-induced acyl-CoA dehydrogenase that controls the lipid saturation level and the fluidity of cellular membranes by transcriptionally regulating a lipid desaturase.
منابع مشابه
Warm up and cool down!
In adaption to shifts in ambient temperature, both prokaryotic and eukaryotic cells maintain physiological homeostasis by adjusting various cellular properties, including membrane lipid fluidity, the capacity to maintain proteostasis and rate of protein synthesis [1]. How cells respond to temperature changes is a fundamental question in cell physiology. Here we briefly review current understand...
متن کاملAssessment of Membrane Fluidity in Individual Yeast Cells by Laurdan Generalised Polarisation and Multi-Photon Scanning Fluorescence Microscopy
Here we describe techniques that we developed for monitoring membrane fluidity of individual yeast cells during environmental adaptation and physiological changes. Multiphoton scanning fluorescence microscopy using laurdan as a membrane probe enables determination whether fluidity changes seen by spectroscopy reflect universal responses or changes only of sub-populations. Yeast membranes are a ...
متن کاملInfluences of growth temperature and preparation of competent cells on efficiency of chemically-induced transformation in Escherichia coli DH5α
It is well known that cellular cultures grown at different temperatures will display altered membrane lipid composition to maintain a relatively constant membrane fluidity across a range of temperatures. One of the proposed theories on the mechanism of chemically-induced transformation is that a higher temperature of the heat-shock step increases the fluidity of the host cell membrane, allowing...
متن کاملIn situ determination of Clostridium endospore membrane fluidity during pressure-assisted thermal processing in combination with nisin or reutericyclin.
This study determined the membrane fluidity of clostridial endospores during treatment with heat and pressure with nisin or reutericyclin. Heating (90°C) reduced laurdan (6-dodecanoyl-2-dimethylaminonaphthalene) general polarization, corresponding to membrane fluidization. Pressure (200 MPa) stabilized membrane order. Reutericyclin and nisin exhibit divergent effects on heat- and pressure-induc...
متن کاملQuality Control of Photosystem II: The Mechanisms for Avoidance and Tolerance of Light and Heat Stresses are Closely Linked to Membrane Fluidity of the Thylakoids
When oxygenic photosynthetic organisms are exposed to excessive light and/or heat, Photosystem II is damaged and electron transport is blocked. In these events, reactive oxygen species, endogenous radicals and lipid peroxidation products generated by photochemical reaction and/or heat cause the damage. Regarding light stress, plants first dissipate excessive light energy captured by light-harve...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Cell
دوره 161 شماره
صفحات -
تاریخ انتشار 2015